Arbutin inowanikwa nekuita glucose ine hydroquinone yakabviswa kubva mubhiribheri mashizha, mashizha ecranberry, mashizha epear, mabheji ebheri, uye blueberries, ayo anowanikwa kumatunhu ane makomo. Iyo molecular chimiro che arbutin ndeye hydroquinone yakanamatira glucose. Arbutin inhibits kuita kwe tyrosinase, iyo inobatanidzwa mukuita kwe melanin synthesis muganda, inodzvinyirira yakawandisa melanin kuunganidza, inoderedza pigmentation, inobatsira kunyange kunze kweganda toni, uye inodzivirira mavara uye freckles. Arbutin yakakamurwa kuita α-mhando uye β-mhando zvichienderana nekuti glucose nehydroquinone zvakabatanidzwa sei.
β-Arbutininogadzirwa nemakemikari synthesis. β-Arbutin ine yakaderera structural kugadzikana pane α-arbutin uye iri nyore kuputswa ne UV maranzi uye kupisa. Nekuda kwehunhu uhu, zvinokurudzirwa kushandisa zvigadzirwa zve skincare ne β-arbutin chete husiku, uye kana ichishandiswa mukati mezuva, inokurudzirwa kushandiswa pamwe chete nesunscreen. Iyo inewo iyo yakashata yekuderedzwa nyore nyore ne intracellular enzymes nekuda kwekudzika kwe intracellular kugadzikana kana ichienzaniswa ne-α-arbutin. Ndiyo α-arbutin inotsiva kukanganisa uku.
- Nhamba yeCAS: 497-76-7
- EC Nhamba: 207-850-3
- Molecular formula: C12H16O7
α-Arbutininogona chete kugadzirwa kuburikidza ne enzymatic synthesis (microbial fermentation). Kusiyana ne-β-arbutin, inoshingirira kuchiedza uye kupisa, saka inogona kushandiswa siku nesikati uye inoshanda zvakatsiga mukati mesero, ichiita kuti ishande uye isina chepfu. Nekubhadhara kukanganisa kwe β-arbutin, yakanyanya kugadzikana uye isingatyoke nyore. α-Arbutin inenge kagumi ine simba kupfuura β-arbutin mukudzivisa melanogenesis. α-Arbutin inhibits tyrosinase kuti kunyange kunze ganda toni uye kuderedza kuchembera makwapa, mburwa mavanga, redness pashure mavanga, uye nezvimwe. Iyo ine zvakare antiseptic uye anti-inflammatory properties.
- Nhamba yeCAS: 84380-01-8
- EC Nhamba : 617-561-8
- EINECS/ELINCS: 440-470-8
- Molecular formula: C12H16O7
Ndezvipi Zvakafanana Pakati peArbutin neAlpha Arbutin?
- Arbutin uye alpha arbutin ndeye glycosylated hydroquinones.
- Alpha Arbutin ndeimwe yemhando mbiri dze arbutin.
- Ose ari maviri anotorwa kubva kune zvakasikwa.
- Vanodzivisa basa re tyrosinase.
- Nokudaro, vanodzivisa kuumbwa kwe melanin.
- Mhando mbiri idzi dzinoderedza kupenya kweganda nemwaranzi yeUV kubva kuzuva.
- Uyezve, arbutin uye alpha arbutin anoshanda seanovheneka ganda.
Ndeupi Musiyano Uripo Pakati peArbutin neAlpha Arbutin?
Arbutin is glycosylated hydroquinone iyo inhibits tyrosinase, ichidzivirira kuumbwa kwe melanin, nepo alpha-arbutin iri imwe yemhando mbiri dze arbutin iyo inopesana nekupisa, inoratidza kugadzikana kwakawanda uye kunyungudika kwemvura yakawanda kupfuura imwe fomu. Saka, uyu ndiwo mutsauko wakakosha pakati pearbutin nealpha arbutin. Iyo yakachengeteka yekumisikidza yekushandiswa kwearbutin maererano nealpha fomu i2%, uye beta fomu i7%.
Iyo pazasi infographic inopa mutsauko uripo pakati pearbutin nealpha arbutin mune tabular fomu yekufananidza-ne-parutivi.
Ko arbutin inoshanda sei paganda rako?
Sezvatinoziva, kana ganda melanocyte richimutswa nekunze ultraviolet mwenje, ivo vanogadzira tyrosinase, iyo inosanganiswa netyrosine mumuviri kuita dopamine, uye pakupedzisira inoumba melanin kuburikidza neREDOX, decomposition uye decarboxylation reactions. Melanin, iyo pigment inokonzeresa ruvara rweganda, inozoendeswa kune basal layer, dermis, epidermis uye imwe ganda chimiro layer, uyezve nekuteura dander kana kutenderera kweropa system. Nekudaro, kana paine melanin yakawandisa, haigone kugadzikiswa nemuviri inokwira mu epidermal layer kuti iite tsvina. Zvimwe zvinongedzo zvakaita sehydroquinone (hydroquinone), arbutin, phenylethylresorcinol, uye azelaic acid zvinogona kuvharisa kusungwa kwe tyrosinase ku tyrosine uye kuvharira melanin.
Arbutin inosunga zvine simba neiyo enzyme tyrosinase inokonzeresa kuumbwa kwe melanin. Ndiyo imwe nzira ine simba kune hydroquinone (iyo yakarambidzwa muEurope neAustralia) asi yakapfava paganda. Kusiyana nehydroquinone, inova chinhu chakasimba chinovhenekera ganda chinogona kuita hukasha paganda, arbutin inzira yakachengeteka uye yakasikwa. Muchidimbu, beta arbutin inoshanda nemakwikwi inhibiting tyrosine. Izvi zvinodzivirira kugadzirwa kwe melanin, zvichiita kuti ganda rako riite serakapfava uye richipenya - pamwe nekuderera kwe hyperpigmentation, mazera ezera, mavara ezuva uye mavanga emburwa.
Nguva yekutumira: Jul-11-2023
