Kana zvasvika kune hutano uye hutano, kuwana izvo zvekuwedzera zvinogona kuita mutsauko wenyika. Keira ari kuzokuudza nezve resveratrol mune ino post nhasi. Resveratrol ine mukurumbira munyika nekuda kweFrench Paradox yakakurukurwa muma1990s, apo zvaitendwa kuti chikonzero nei vanhu vekuFrance vanodya chikafu chine mafuta akawandisa vasingatambudzike kurwara nemoyo nekuti resveratrol iri muwaini tsvuku yavanowanzo kunwa. .
Kubva ipapo, resveratrol yakaramba ichiwanikwa nekuda kwehutano hwayo hunogona kubatsira, kusanganisira antioxidant, anti-inflammatory, anticancer, uye cardiovascular protective effects.
Chii chinonzi resveratrol?
Resveratrol, iyo isiri-flavonoid polyphenol organic compound, inonzi antitoxin inogadzirwa nemiti yakawanda kana ichikurudzirwa, nemakemikari formula C14H12O3. Muna 1940, nyanzvi yeJapan MichioTakaoka akatanga akasarudzika resveratrol kubva kuVeratrum album mumhuri yemaruva, uye akazoiwana kubva kuPolygonum cuspidatum mumhuri yepolygonum muna 1963. Inogona kugadzirwa mumashizha emuzambiringa nematehwe emazambiringa uye i bioactive ingredient muwaini uye. muto wemazambiringa. Inotorwa nyore nyore nemuromo uye inobudiswa muweti uye chigaro mushure memetabolism. In vitro uye yemhuka kuedza kwakaratidza kuti resveratrol ine antioxidant, anti-inflammatory, anticancer uye cardiovascular protective effects.
Resveratrolinoparadzirwa zvakanyanya mumiti, uye kubva muna 2021, yakawanikwa mumiti inopfuura makumi manomwe kubva kumhuri makumi maviri neimwe, Kunyanya, itis inowanikwa muVitis, Ampelopsis, Polygonum, Arachis, Cassia, Sophora, Veratrum, Veratrum uye Eucalyptus. Miti yakajairika ine resveratrol inosanganisira mazambiringa, knotweed, nzungu, cassia, etc. Iyo kemikari synthesis nzira ye resveratrol ine nyore uye yakakura maitiro, goho repamusoro uye mutengo wakaderera wekugadzira wakashandiswa pakugadzirwa kwemaindasitiri, kuitira kuti kutora resveratrol hakuna. kureba zvichienderana nekutorwa uye kupatsanurwa kubva kumiti. Iyo synthesis process ye resveratrol inonyanya kushandisa Wittig reaction kuona kupatsanurwa kwemaviri benzene mhete, uye goho rinogona kusvika kupfuura 50%.
Chii chinokonzera resveratrol?
- Anti-kuchembera
Mumakore achangopfuura, zvakaonekwa kuti akawanda polyphenols ane akakosha anti-oxidation uye anti-yemahara radical mhedzisiro.
Seyakasikwa antioxidant, resveratrol ine yakasimba yekuzvibvisa uye anti-lipid peroxidation, uye kunyange ichienzaniswa neyechinyakare antioxidants senge vhitamini C, butylhydroxytoluene, tocopherol, resveratrol ine zviri nani antioxidant mhedzisiro.
Resveratrolinoshandisa iyo antioxidant effect kunyanya kuburikidza nekutsvaira kana kuvharidzira mahara radicals, inhibiting lipid peroxidation, kugadzirisa basa rema enzymes ane chokuita neantioxidation nedzimwe nzira.
Resveratrol inoramba kuchembera kunokonzerwa nelipid peroxidation inokonzerwa nemahara radicals uye metabolites yavo. Panguva imwecheteyo, resveratrol inobvisa mahara radicals, inoderedza zviri muH₂O₂ muganda, inovandudza basa reATPase, uye nekudaro ine mhedzisiro yekunonoka kuchembera kweganda.
- Dzora shuga yeropa
Chirwere cheshuga ndicho chirwere chisingaperi chisingaperi, asiwo chinodzivirirwa nyore nyore, asi nekuda kweizvi kazhinji regai vanhu vatore zvishoma, dambudziko rechirwere cheshuga, ndiro arteriosclerosis, kunze kwekuwedzera zvakanyanya mukana wemyocardial infarction, sitiroko, kana inokanganisa itsvo microvessels, inozokonzeresa kutadza kweitsvo, saka maitiro ekudzora shuga yeropa akakosha kuhupenyu.
Muchidzidzo chiduku, resveratrol (150 mg zuva nezuva kwemazuva 30, DSM proprietary component resVida) yakavandudza mazinga ehuga eropa (ne4.2%) uye insulin mazinga (ne13.7%) muvanhu vane uremu.
- Anti-tumor, anti-cancer
Resveratrol ine yakakosha inhibitory mhedzisiro pahepatocellular carcinoma, kenza yemazamu, kenza yekoloni, kenza yemudumbu, leukemia uye mamwe masero emamota. Dzimwe nyanzvi dzakasimbisa kuti resveratrol ine pachena inhibitory mhedzisiro pamasero emelanoma neMTT nzira uye kuyerera kwe cytometry.
Zvinonzi resveratrol inogona kuwedzera cancer radiation therapy, kutamba "1+1> 2" mhedzisiro, uye nekumisa basa rekenza stem maseru. Asi kusvika pari zvino, nekuda kwekuoma kweiyo anti-tumor mechanic ye resveratrol, vaongorori havasati vasvika pakubvumirana pamaitiro ayo ekuita.
- Mamwe mabasa
Resveratrol zvakare ine antibacterial, antioxidant, immunomodulatory, antiasthmatic uye zvimwe zvipenyu zviitiko. Resveratrol inotsvakwa zvakanyanya nekuda kweayo akasiyana biological zviitiko.
Nzira yekutora resveratrol?
- Natural plant extraction method
Resveratrol yakabviswa uye yakacheneswa kubva kumazambiringa, knotweed uye nzungu. Iyo crude extraction tekinoroji inonyanya kusanganisira organic solvent extraction method, alkali extraction method uye enzyme extraction method, microwave yakabatsira nzira yekubvisa, CO2 supercritical extraction, ultrasonic yakabatsira kubvisa uye dzimwe nzira itsva dzinoshandiswawo. Chinangwa chikuru chekucheneswa ndechekuparadzanisa resveratrol cis, trans isomer uye resveratrol Xib kubva kune yakabviswa resveratrol mbishi kuti uwane trans-resveratrol. Nzira dzinowanzo shandiswa dzekuchenesa chromatography, silica gel column chromatography, nhete chromatography, high performance liquid chromatography zvichingodaro.
- Synthesis nzira
Nekuda kweiyo yakaderera yemukati ye resveratrol muzvirimwa uye yakanyanya kudhirowa mutengo, kushandiswa kwemakemikari, biological uye genetic engineering nzira yekuwana resveratrol yave nzira yakakosha mukuvandudza maitiro. Perkin reaction, Hech reaction uye Witting-Hormer reaction inzira dzemakemikari dzakakura dzekubatanidza resveratrol, ine goho re55.2%, 70% uye 35.7%, zvichiteerana. Kushandisa genetic engineering tekinoroji kudzora kana kuvandudza biosynthesis nzira ye resveratrol kuti uwane yakakwirira-goho chirimwa mitsara; Chibereko che resveratrol chakawedzerwa ne 1.5 ~ 3.0 nguva ne mutagenesis nedzimwe nzira.
Aogubio ikambani inoshanda mukugadzira uye kugovera zvinhu zvine chekuita nemishonga, zviwanikwa uye zvinotorwa zvezvirimwa, zvinosanganisira zvinovaka muviri zvekugadzira zvekuwedzera kwevanhu. Isu tinotarisa pamishonga uye zvigadzirwa zvemishonga yemishonga, chikafu, nutraceutical uye cosmetic industries, uye takazvipira kupa vatengi vane hutano hwepamusoro uye hunobudirira.
HUNHU HWAMUNHU:
Nzvimbo yedu yakashongedzerwa nerabhoritari inoshandisa mamiriro-ye-iyo-gasi chromatography kuti iedze zvakasimba kuchena uye simba rezvigadzirwa zvedu; kuve nechokwadi chekuti vatengi vedu vanowana zvigadzirwa zvemhando yepamusoro nguva dzese.
MABATIRO EVATENGI:
Kuchengeta chinangwa chedu chekuzadzisa Gwaro reKugutsikana Kwekugutsikana, timu yedu yakazvitsaurira inogara yakagadzirira kupa mumwe nemumwe wevatengi vedu indasitiri inotungamira sevhisi yevatengi mune yega yega yeodha.
Kana iwe uchida kuziva nezve kana kutenga mhando yepamusoro ye resveratrol, ndapota taura nakayla.
Kubata: Keira Zhang
Email: sales06@aogubio.com
Tel: +86 18066856327
Nguva yekutumira: Jan-08-2024
