Benfotiamine ndeyekuwedzera kwekudya kunoshandurwa mumuviri kuita thiamine (vitamin B1). Thiamine inobatsira muviri wako kushandura chikafu kuita simba uye yakakosha pakushanda kwehuropi. Vamwe vanhu vanoshandisa benfotiamine kukwidza thiamine nekuti inonzi ine bioavailable yakawanda.Izvi zvinoreva kuti inosvika muropa nekukasira uye inoburitsa huwandu hwethiamine mumuviri.
Nokuti ine antioxidant uye anti-inflammatory properties, benfotiamine inogonawo kubatsira kune diabetic neuropathy (marwadzo etsinga) uye chirwere cheAlzheimer.
Utano hunobatsira hwebenfotiamine
1. Diabetic neuropathy
Benfotiamine therapy inoratidzika seyo nzira yekudzivirira chirwere cheshuga nephropathy, dambudziko rakakomba rechirwere cheshuga, rinosangana nenjodzi huru yechirwere chemoyo uye kufa. High glucose concentrations inotungamirira pakuunganidza triosephosphates; izvi zvinotungamirira ku biochemical dysfunction uye pakupedzisira kukura kwechirwere cheshuga nephropathy.
Zvidzidzo zvepreclinical mumakonzo zvakaratidza kuti benfotiamine inodzivirira kuunganidzwa kwe triosephosphates muchirwere cheshuga uye nokudaro inhibisa kukura kwenephropathy.
2. Kuvandudzwa kwekuziva muchirwere cheAlzheimer
Zvidzidzo zvepreclinical zvakaratidza kuti benfotiamine inopa mhedzisiro inobatsira pakukanganisa kwekuziva muchirwere cheAlzheimer. Benfotiamine yakaratidzwa kuderedza amyloid deposition mumhando dzemhuka dzechirwere cheAlzheimer. Zvakadaro, mhedzisiro iyi haina kuratidzwa muvanhu. Chikamu chechipiri chekuedza kwekliniki ikozvino chiri kuongorora kana benfotiamine inogona kumisa kuderera kwekuziva kune varwere vane hunyoro hwekunzwisisa kukanganisa.
3. Kukurira kupindwa muropa nedoro
Kugara kunwa doro kunobatanidza nekushayikwa kwakanyanya kwezvinovaka muviri zvakakosha uye mavhitamini. Kushaikwa kwe thiamine kunokonzerwa nedoro kunoratidzwa neurological syndromes nekuda kwekurasikirwa kunofambira mberi kwepakati uye peperipheral white matter. Kunyangwe kutsiva kwethiamine kwakakosha kune varwere vane doro-induced central nervous system kukuvara, benfotiamine haina kuratidza kushanda mukuyambukira mukati mepakati tsinga system kubva kunharaunda.
4. Benfotiamine yekusvuta
Kusvuta kunotungamirira kune endothelial dysfunction, chiitiko chekutanga muhutano hwemwoyo. Izvi zvinowedzerwa neoxidative kusagadzikana uye kuzvimba. Muchidzidzo chekutanga pamakonzo, benfotiamine yakawanikwa kudzivirira nicotine-induced vascular dysfunction. Muedzo wakaitwa pavazvipiri vane hutano wakaratidza kuti kurapwa kwenguva pfupi nebenfotiamine kunogona kudzoreredza macrovascular function muvanoputa vane hutano.
5. Kudzivirira itsvo
Dhata kubva kuzvidzidzo mumakonzo inoratidza kuti benfotiamine inopa chiito chekudzivirira kune peritoneal membrane uye yakasara itsvo mu peritoneal dialysis uye uremia. Maererano neongororo yakabudiswa mu Journal of the American Society of Nephrology, kuwedzerwa kwe benfotiamine mukudya kunotungamira mukuwedzera kwe transketolase chiitiko uye kuderera kwekutaura kwepamusoro glycation end zvigadzirwa uye receptor yavo.
Chidzidzo chakaitwa naUstuner et al. rakabudiswa muTissue and Cell yakawana kuti benfotiamine supplement inogona kubatsira mukuderedza antibiotic-induced nephrotoxicity kuburikidza nekuvandudzwa kweoxidative kusagadzikana uye kuzvimba kwerenal tubular masero.
6. Antitumor inogona
In vitro zvidzidzo zvinoratidza kuti benfotiamine inogona kumisa leukemia nenzira inonzi paraptosis cell death. Paraptosis imhando yezvakarongwa sero kufa iyo inosanganisira cytoplasmic vacuole formation. Ongororo yeSero tsika nevaongorori veKanazawa University kuJapan yakawana kuti benfotiamine inhengo inovimbisa kune acute myeloid leukemia varwere vasingakodzeri kuwana standard chemotherapy. Vakaonawo kuti benfotiamine yakaratidza synergistic chiitiko ne cytarabine, chemotherapeutic agent, kubvisa myeloid leukemia masero.
7. Antioxidant properties
Benfotiamine zvakare ine simba antioxidant ine anti-inflammatory properties iyo inogadzirwa kuburikidza nekuvharidzirwa kweprostaglandin uye leukotriene synthesis.
Dosage: Yakawanda Sei Benfotiamine Yandinofanira Kutora?
Gara uchitaura nemupi wehutano usati watora chekuwedzera kuti uone kuti iyo yekuwedzera uye dosi inokodzera zvaunoda iwe pachako.
Hapana yakachengeteka kana inoshanda dosage kurudziro yakatemerwa benfotiamine semushonga wechero mamiriro.
Zvidzidzo zvakawanda muvanhu vane chirwere cheshuga vakashandisa dosages ye300 mg kaviri pazuva. Mimwe miedzo yakashandisa madosi akakwira se900 mg pazuva pasina matambudziko akakosha.
Kana iwe uchida kuedza benfotiamine supplements, taura nemutarisiri wako wehutano. Vanogona kukutungamira kuti zvakakukotsera here uye nekukubatsira kuona dosi rakakodzera.
Nguva yekutumira: Kubvumbi-04-2023
